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In mid-2024, the Endocrine Society warned that online prescribing of compounded GLP-1s poses patient safety risks and undermines public confidence in obesity care. The organization called for stricter verification of clinicians and for oversight of digital compounding networks that have limited traceability or pharmacovigilance. Their concern echoed that of the FDA , which, after investigating multiple adverse-event reports linked to unapproved semaglutide, issued formal warnings to both compounders and telehealth distributors

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The bigger picture: Retatrutide represents the next evolution in metabolic medicine